Five ladies have moved in to the neighborhood to live on the same floor. Among them, hotel manager Zhu Zhe, Yu Chu Hui who's only been working for a few years and He Min Hong share a flat together. The mysterious Fang Zhi Heng and Ye Zhen Zhen who engages in life science research live in the other two units. Five women from different backgrounds have unsatisfactory experiences when it comes to their career, family and love life. Fang Zhi Heng is a suspicious character due to her actions. Ye Zhen Zhen who got used to having special privileges finds that the workplace is inexplicably hostile. Yu Chu Hui is too smart for her own good. She'll resort to little tricks to get ahead only to learn her lesson after taking a fall. Work seems to be going smoothly for Zhu Zhe, yet her opportunities to move up is limited by her weak academic qualifications. He Min Hong who is quite naive finds herself doing the wrong things in her attempts to do good. Faced with all kinds of challenges, they go from putting up defences to opening their hearts. In the city of Shanghai, they have each other to rely on in their journey of growth.